How much weight can you lose with Mounjaro? 🤷🏻‍♂️👨🏻‍⚕️ #mounjaro #doctor #obesity



The average weight loss is 22% of your body weight over the course of 72 weeks, so a little more than a year. This number is based on the 15 mg dose of tirzepatide (Mounjaro). There are many stories of people, especially on TiKTok, of people losing anywhere from 60 to more than 100 pounds. Charles Barkely for example, lost 60 pounds. It took Tara Rothenhoefer about 2 years to lose 176 pounds. The amount of weight you lose depends on several factors, mainly the dose of tirzepatide (AKA Mounjaro), diet, and amount of exercise.

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25 COMMENTS

  1. Excellent breakdown of Mounjaro’s potential, Doctor! Understanding the metrics of these powerful new medications is key for patient planning.

    Your video reminds us of one universal truth: While the drug is powerful, the need for an injection or a low-efficiency oral pill always adds a layer of complication. It feels like the medication has to pass a difficult 'delivery challenge' before it can even start its job!

    We specialize in the science of advanced pharmaceutical delivery—specifically focusing on engineering oral formats that achieve near-instantaneous systemic access. The goal is to deliver injection-level efficiency without the needle or the digestive hurdle.

    What do other viewers think? If a medication offered the same results as an injection, but was a simple, quick-dissolve format, would you switch instantly? What's the biggest hassle in your current medication routine?

  2. Doc just said 'depending on the dose'. Is this correct? Other info suggests as long as you continue to have appetite suppression the dose isn't a deciding factor. It's this not true?

  3. Im from manjaro on 3 months now i started 2.5 then 5mg i stayed 2 months so in total is 19kg until now i just order 7.5mg im on the diet i started gym as well and i started do fasting 12h as well i fell amazing my goal is to reach 85kg and after i will stop whit manjaro

  4. Im diwn 72 lbs in 6 months. I think theres something wrong though. Losing to fast. At furst 19 lbs 1st week, than 15 lbs, than on avg about 8 lbs a week. I do have severe gastrointestinal issues from it. I can barely eat, and gete severe gas pains in my liwer abdomen and dugestive issues. I can only do a bowel movement abiut 1x every 4 days. Very painful. The dr saud i have sliw emptying and shoukd stop being it is paralyzing my intestines. I want to do it to lise 50 more lbs to get to 150. I have nit exercised at all being im disabked. I have autoimmune dusease and need 2 total knee replacements, back and neck syrgery as i develooed degenerative didc disease and osteoarthritis. If you go on thus id say sit with a nutritionis to do a liw residue diet with plenty of oritein, vitamins, and less foid wuth alit if nutrutional content. I have a lit if muscle loss and scoliosus from this. I dropped to fast and have alit of excess skin in my chin, arms and legs. Im niw in physical therapy to build muscle as its painful to walk. Bone pain. I need b12, vutamin d injections. Vutamins are crucual on thus diet. Once i get under 200 and finish physical therapy i pland to get back into bodybuilding like in my 20s to build up muscle, reshape my body, but i will need surgey for abdomen chest and arms. Its easy to become anorexic on this as you literally never feel hungry. Goid luck. I plan to pist vudeos of my journey. My profile photo is me at 272.

  5. Aug 30, 2025 I started taking a statin & Monjaro. On my 8th dose I had a hard raised, hot, red spot the size of 2 inches. I thought I didn't clean it properly. The 9th shot I did on top of my thigh as shown in the pamphlet (hurt like hell). I also had a bigger reaction at the injection site. A 5 inch red spot. Hot, hard and lasted for over 2 weeks!
    I saw my PRN today, she wants me to keep taking it even though my A1c is 6, and lost 16 pounds. To be honest, I'm scared. I've had horrible joint pain while taking Monjaro & a statin at the same time.
    A friend of mine is a RN and she said I shouldn't take Monjaro any more because it looks like I'm allergic to it.

  6. I was 301 on Nov 20, 2024. fixed diet and started walking then on new years eve I started weekly mounjaro. now Oct 20, 2025 I'm 210lbs. 90lbs down (though I lost about 10 on my own before starting the shots).

  7. Morning. Week 20 and second week on 2.4ml dose per week. After sticking to the rules (drinking plenty of water ect) I initially lost 2 stone. I stuck on that loss from ten weeks. Today I weighed in and I have put (one Stone on)😢 what’s going wrong 😑

  8. I am on week 20 of manjaro and the first month I was on the the 2.5ml weekly dose. I started off okay, But the last 10 weeks I have lost nothing. I drink water all day. Sometimes with zero calories fruit juice in it to flavour it. I eat sensibly, But do little exercise . due to health issues.i did lose 2 stone to start with, But sadly nothing since. I am going to ask for the higher weight in two weeks time. So in the last 10 weeks I have lost nothing ☹️🙏

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